Vol 2-2 Commentary

Commentary: Bilateral Ballism Following Streptococcal Infection, Associated with Psychiatric Disorder and Purpura

Antonio N Gomez-Valdes*

Department of Internal Medicine, Havana University School of Medicine, Havana, Cuba

DOI: 10.29245/2689-9981/2018/2.1131 View / Download Pdf
Vol 2-2 Research Article

Fungal Infections in HIV-positive Peruvian Patients: Could the Venezuelan Migration Cause a Health Warning Related-infectious Diseases?

Jeel Moya-Salazar1,2*, Richard Salazar-Hernández3, Victor Rojas-Zumaran2, Wanda C. Quispe3

1School of Medicine, Faculties of Health Science, Universidad Privada Norbert Wiener, Lima, Peru

2Pathology Department, Hospital Nacional Docente Madre Niño San Bartolomé, Lima, Peru

3Cytopathology and Genetics Service, Department of Pathology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru

In patients with human immunodeficiency virus (HIV), opportunistic infections occur that could compromise the health of patients. In order to determine the frequency of fungal opportunistic and superficial infections in HIV-positive men-who-have-sex-with-men (MSM) patients at the Hospital Nacional Guillermo Almenara, we conducted a cross-sectional retrospective study. We include Peruvian patients >18 years-old, derived from infectious or gynecological offices, with or without antiretroviral treatment.

One hundred thirteen patients were enrolled (36.7±10, range: 21 to 68 years), which 46 (40.7%) has an opportunistic fungal infection, mainly by candidiasis (23.9%), pneumocystosis (8.7%), and cryptococcosis (6.5%). Six (13%) patients had fungal coinfections, mainly by oral candidiasis and ringworm (Tinea pedis) (4.3%), and opportunistic infections have an incidence of 15.9%. Of the 17 cases of dermatophytosis, 12 (70.6%) were from Tinea pedis, 5 (29.4%) from Tinea corporis, 3 (17.6%) from Tinea unguium, and two (11.8%) from Tinea versicolor. We found significant difference between the year of HIV-infection and the year of fungal infection (p=0.001).

The frequency of opportunistic fungal infections was determined in the fourth-and-six percent of Peruvian MSM HIV-positive patients, where candidiasis, pneumocystosis, and cryptococcosis were the most frequent. We raise the importance of fungal infections in the current framework of Venezuelan migration, since this could be a new risk factor and imply changes in incidence rates, which implies new challenges for Peruvian Public Health.

DOI: 10.29245/2689-9981/2018/2.1132 View / Download Pdf
Vol 2-2 Commentary

Commentary on, "Generation of Three-dimensional Human Neuronal Cultures: Application to Modeling CNS Viral Infections"

Leonardo D’Aiuto1*, Nicholas Radio2, Vishwajit L. Nimgaonkar1

1Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O’Hara Street, Pittsburgh, PA, US

2Thermo Fisher Scientific, Cellular Imaging and Analysis, 100 Technology Drive, Pittsburgh, PA, US

DOI: 10.29245/2689-9981/2019/2.1137 View / Download Pdf
Vol 2-2 Commentary
Vol 2-2 Commentary

Commentary: "The Development of an Ideal Antibiotic Compound: A Fairy Tale or a Possible Reality?"

Márió Gajdács

Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, Szeged, Hungary

DOI: 10.29245/2689-9981/2019/2.1139 View / Download Pdf